| Description: |
Duchenne and Becker muscular dystrophies (DMD and BMD) are X-linked disorders caused by mutations in the DMD gene, which lead to abnormalities in the large cytoskeletal protein dystrophin. This DMD/BMD assay amplifies 24 exons and two promoter regions of the DMD (also called Dystrophin) gene, which comprise the locations in which the vast majority of mutations are identified. At least one of these exons is missing and, therefore, will not amplify in >98% of deletions. |
