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| Test Code: |
EBVQP |
| Description: |
Epstein-Barr virus (EBV), or human herpesvirus 4, is a gamma-herpesvirus that infects more than 95% of the world’s population. The most common primary infection with this organism is acute infectious mononucleosis, which primarily affects adolescents and young adults. Classic symptoms include sore throat, fever, and lymphadenopathy. Infection with EBV in younger children usually is asymptomatic or mild. However, EBV also is a human tumor virus, the first virus associated with human malignancy. Infection with EBV is associated with lymphoproliferative disorders, especially in immunocompromised hosts, and with a variety of tumors including nasopharyngeal carcinoma and Burkitt lymphoma. |
| Indications: |
This test is used to detect EBV nucleic acid and is most frequently used in diagnosis or monitoring of serious EBV-associated illnesses, including post-transplant lymphoproliferative disorder, nasopharyngeal carcinoma, and AIDS-related brain lymphoma. |
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