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| Test Code: |
RIST |
| Description: |
The Ristocetin Co-Factor activity is a functional assay for vW factor (vWF). vWFis secreted from endothelial cells and promotes platelet adhesion to the site of vessel injury by attaching to the glycoprotein Ib/IX (GPIb/IX) platelet receptor. vWF also stabilizes and protects factor VIII. Von Willebrand disease is the most common inherited bleeding disorder. Levels of vWF are lower in blood type O patients (as compared to blood types A, B, or AB). |
| Indications: |
Bleeding disorder, suspected von Willebrand disease |
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