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| Test Code: |
LUPUS |
| Description: |
The PTT LA reagent is a PTT reagent with low phospholipid content optimized for detection of lupus anticoagulants. However, a prolongation of the PTT LA reagent can also be due to other causes (disfibrinogenemia, heparin, intrinsic factor deficiencies, or factor inhibitors). When a PTT LA is prolonged, then a PTT inhibitor screen (mixing study) is performed using PTT LA reagent, and if this shows an inhibitor then a phospholipid neutralization test is performed to determine whether a lupus anticoagulant is present. |
| Indications: |
Suspected antiphospholipid syndrome, evaluation of prolonged aPTT |
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