| Description: |
Amniocentesis and chorionic villus sampling is performed as part of prenatal evaluation for a variety of inherited genetic disorders. It is important to exclude maternal cell contamination. Therefore, the laboratory performs a multiplex PCR to detect short tandem repeat markers, which provide a genetic “finger-print” of any given individual. By comparing the identifying marker in the sample with the maternal sample, contamination of the amniotic fluid specimen of >1% maternal cells can be identified. |
